Segments in this Video

Cancer in Children (03:01)


At Great Ormond Street Hospital, parents and doctors strive for a balance between treatment and quality of life. Dr. Olga Slater informs Barnabus' parents the pathology report will be ready later this morning. (Credits)

Consultation with Cardiothoracic Surgeon (03:06)

Slater tries to be empathetic towards parents, but needs them to have all the information. After consulting with Dr. Nagarajan Muthialu, Slater opts for chemotherapy first. Barnabus will receive four drugs in succession and then surgery to remove the tumor.

Five Year Old Girl with Brain Tumor (02:16)

Dr. Owase Jeelani meets with Chaine's parents to propose a treatment plan and answer questions. Possible complications to the surgery include: decreased right side motor function, loss of speech, loss of comprehension and seizures.

Preparing for Surgery (03:12)

Dr. Jeelani operates on Chaine. A biopsy of the tumor is sent to pathology and he removes as much of the tumor as he can.

Types of Brain Tumors (03:24)

Because scientists do not know why these tumors occur, it is impossible to control the outcome. A week later, Dr. Penelope Brock meets with the Chaine and her parents to give the results of the biopsy and treatment options. The Milan Protocol is recommended.

Options for Treatment (03:59)

The protocol prescribes chemotherapy, radiotherapy and stem cell rescue in rapid succession— it is very intense. Chaine's parents debate whether or not to consent to the treatment because of its low success rate.

Difficult Decisions (03:24)

Increased toxicity because of the treatment can kill the child— Dr. Brock elaborates that aggressive therapies are necessary to increase cure rates. A week later, Chaine's parents agree to the Milan Protocol because it is their child's best shot at survival. Chemotherapy begins.

Signing Surgical Consent Forms (02:05)

After four months of chemotherapy, Barnabus can be operated on to remove his tumor. Dr. Agostino Pierro consults with the parents, explains the risks, and prepares for surgery.

In Surgery (03:21)

During the operation, Dr. Pierro needs to remove part of another rib. Barnabus will need chemotherapy and radiotherapy. In initial treatments, survival rates were 20 percent, but they have risen to 70 percent.

Luna's Rare Brain Tumor (02:00)

Luna's treatments have included: surgeries, chemotherapy and radiation. Dr. Anthony Michalski reviews recent scans with the oncology department.

Not Good News (02:32)

Another tumor has emerged in Luna's brain. Dr. Michalski consults with Luna's parents about the realities of chemotherapy. He is hopeful it might give Luna some time.

Second Phase of the Milan Protocol (04:08)

Dr. Brock, Dr. Michalski, and Chaine's parents discuss her potential quality of life after high dose radiation. She will be a different child, however Dr. Michalkski believes the change will not be as drastic as Chaine's parents fear.

High Dose Radiation Session (02:04)

Dr. Brock explains that Chaine would most likely have excelled in school, but by giving her this treatment, she will possess development delays. Chaine will receive two doses of radiotherapy every day for the next four weeks.

Luna Begins Etoposide (03:10)

Luna visits several prominent oncologists, but none offer a cure. Her parents discover the Burzynski treatment online, but her doctor disagrees with the therapy and does not understand the side effects. After two months on chemotherapy, Luna's tumor has not grown.

Tumor is Stagnant (02:59)

Dr. Michalski wants Luna to remain on the Etoposide and not change to Burzynski treatment. Luna's mother begins fundraising efforts to raise the 100,000 pounds necessary to start the trial.

Two Months Later (04:03)

Luna's parents decide to pursue the Burzynski treatment over Etoposide. Her mother explains the decision to Michalski, saying the chemotherapy is a palliative measure which will not cure the cancer.

Four Weeks of Radiotherapy (03:39)

Dr. Brock is pleased with Chaine's latest scan and shares the news with her parents. The next step in the Milan Protocol could potentially kill Chaine, and Dr. Brock wants to ensure that it is a team effort.

Luna Begins the Burzynski Treatment (02:21)

Luna goes to the emergency room with high sodium and low potassium levels. A recent MRI shows the tumor is growing. Dr. Michalski tells Luna's mother she needs to make a decision about the treatments efficacy.

Reviewing Luna's Scans (03:35)

Dr. Michalski tells Luna's mother the tumor is inoperable. She ceases the Burzynski treatment, but searches for other options. Chaine begins high dose chemotherapy and Barnabus starts radiation.

Credits: A Difficult Line: Great Ormand Street, Series 2 (00:44)

Credits: A Difficult Line: Great Ormand Street, Series 2

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A Difficult Line: Great Ormond Street, Series 2

Part of the Series : Great Ormond Street, Series 2
DVD (Chaptered) Price: $300.00
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A look at Great Ormond Street Hospital's oncology department, following doctors as they face challenging ethical decisions about treating children with some of the rarest and most complex cancers in the country. Doctors must decide how to act in the best in terest of their patients whilst handling relationships with the children's families. A BBC Production.

Length: 60 minutes

Item#: BVL115643

ISBN: 978-1-63521-078-1

Copyright date: ©2012

Closed Captioned

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